Figure 5.

Resistance, growth, and competition advantages of cpKP harboring bla_KPC-carrying plasmids of different Inc groups

A. Boxplot showing the numbers of classes of antibiotics that different subgroups of cpKP isolates were resistant to. The P values were obtained using Kruskal–Wallis, a non-parametric test for the comparison of multiple groups. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. B. Bacterial growth curves of different subgroups of cpKP isolates. The dashed line indicates the time point at 1 h, when bacteria were at the logarithmic growth phases; corresponding OD₆₀₀ values (mean ± standard error) were shown in the embedded bar plot. C. Bacterial in vitro competition experiments. Shown were the ratio of Ct values (mean ± standard error) between each two cpKP isolates at 24 h, 48 h, and 72 h, respectively.