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. 2023 May 15;14:1147858. doi: 10.3389/fneur.2023.1147858

Table 3.

Differences between female and male ischemic stroke patients in terms of short-term and 1-year outcomes.

Outcome measure Overall (n = 7,300) Women (n = 1,406, 19.3%) Men (n = 5,894, 80.7%) P-value
mRS score at 90 days
0 2,470 (43.8) 382 (33.6) 2,088 (46.4) < 0.001
1 799 (14.2) 119 (10.5) 680 (15.1)
2 541 (9.6) 104 (9.2) 437 (9.7)
3 739 (13.1) 191 (16.8) 548 (12.2)
4 451 (8.0) 120 (10.6) 331 (7.4)
5 328 (5.8) 105 (9.2) 223 (5.0)
6 308 (5.5) 115 (10.1) 193 (4.3)
mRS category at discharge
Good (mRS 0–2) 4,279 (58.6) 664 (47.2) 3,615 (61.3) < 0.001
Poor (mRS 3–6) 3,021 (41.4) 742 (52.8) 2,279 (38.7)
mRS category at 90 days (n = 5,636, 77.2%)
Good (mRS 0–2) 3,810 (67.6) 605 (53.3) 3,205 (71.2) < 0.001
Poor (mRS 3–6) 1,826 (32.4) 531 (46.7) 1,295 (28.8)
Poor outcome (mRS 3–6) at 90 days (n = 1,826)
 Age < 46 years 312 (17.1) 42 (7.9) 270 (20.8) < 0.001
 Age 46–55 years 382 (20.9) 45 (8.5) 337 (26.0)
 Age 56–65 years 450 (24.6) 110 (20.7) 340 (26.3)
 Age >65 years 682 (37.3) 334 (62.9) 348 (26.9)
Mortality rate at discharge 144 (2.0) 38 (2.7) 106 (1.8) 0.03
Mortality rate at 90 days 308 (5.5) 115 (10.1) 193 (4.3) < 0.001
1-year outcomes
Recurrent stroke (ischemic or hemorrhagic) 132 (2.3) 28 (2.4) 104 (2.3) 0.85
Post-stroke MI (fatal or non-fatal) 44 (0.8) 9 (0.8) 35 (0.8) 0.99
All-cause mortality 372 (6.5) 139 (11.7) 233 (5.1) < 0.001
Post-stroke cardiac arrest 94 (1.7) 37 (3.2) 57 (1.3) < 0.001
Post-stroke cardiac revascularization (CABG or PCI) 44 (0.8) 7 (0.6) 37 (0.8) 0.46
Major cardiac adverse event (MACE) 561 (7.7) 177 (12.6) 384 (6.5) < 0.001
Total MACEs over 5 years
0 events 6,739 (92.3) 1,229 (87.4) 5,510 (93.5) < 0.001
1 event 439 (6.0) 134 (9.5) 305 (5.2)
2 events 119 (1.6) 43 (3.1) 76 (1.3)
3 events 3 (0.1) 0 3 (0.1)

mRS, Modified Rankin Scale; MI, myocardial infarction; CABG, coronary artery bypass graft; PCI, percutaneous coronary intervention; MACE, major adverse cardiovascular event.