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. 2023 May 15;13:1192512. doi: 10.3389/fcimb.2023.1192512

Table 2.

Treatment and outcomes of the regdanvimab and supportive care groups, total cohort.

Variables Regdanvimab (n = 1,095) Supportive care (n = 1,119) P value
Regdanvimab
 Regdanvimab treatment 1,095 (100) 0 (0.0) NA
 Interval from symptom onset to regdanvimab, days 3.6 ± 2.0 NA NA
 Interval from admission to regdanvimab, days 1.1 ± 1.3 NA NA
Remdesivir, steroid, and antibiotics
 Remdesivir treatment 128 (11.7) 151 (13.5) 0.201
 Interval from admission to remdesivir, days 2.5 ± 2.1 3.3 ± 3.1 0.006
 Steroid treatment 183 (16.7) 247 (22.1) 0.001
 Interval from admission to steroid, days 2.5 ± 2.7 3.1 ± 3.1 0.042
 Antibiotic treatment 50 (4.6) 74 (6.6) 0.036
 Interval from admission to antibiotics, days 1.7 ± 2.1 4.2 ± 3.7 <0.001
Outcome measures
 O2 supplementation via nasal prong 201 (18.4) 303 (27.1) <0.001
 Interval from admission to nasal prong, days 17.5 ± 7.4 16.1 ± 8.2 <0.001
 Composite outcome for progression to severe disease 44 (4.0) 90 (8.0) <0.001
 Interval from admission to composite outcome, days 20.3 ± 3.4 19.7 ± 4.5 <0.001
 O2 supplement via facial mask 10 (0.9) 34 (3.0) <0.001
 Interval from admission to facial mask, days 4 (3–5) 5 (3–7) 0.002
 O2 supplement via HFNC 26 (2.4) 40 (3.6) 0.097
 Interval from admission to HFNC, days 3 (1–5) 5 (2–7) <0.001
 Referral to tertiary care center 20 (1.8) 57 (5.1) <0.001
 Interval from admission to referral, days 4 (2–6) 5 (3–8) 0.001
Live discharge after recovery without referral 1075 (98.2) 1058 (94.5) <0.001
 Interval from admission to discharge, days 10.3 ± 3.7 12.3 ± 12.5 <0.001
In-hospital mortality during follow-up period 0 (0.0) 4 (0.4) 0.125

Data are expressed as the number (%) of patients, mean ± SD, or median (IQR) unless indicated otherwise.

NA, not applicable; HFNC, high flow nasal cannula; SD, standard deviation; IQR, interquartile range.