Table 2.
Variables | Regdanvimab (n = 1,095) | Supportive care (n = 1,119) | P value |
---|---|---|---|
Regdanvimab | |||
Regdanvimab treatment | 1,095 (100) | 0 (0.0) | NA |
Interval from symptom onset to regdanvimab, days | 3.6 ± 2.0 | NA | NA |
Interval from admission to regdanvimab, days | 1.1 ± 1.3 | NA | NA |
Remdesivir, steroid, and antibiotics | |||
Remdesivir treatment | 128 (11.7) | 151 (13.5) | 0.201 |
Interval from admission to remdesivir, days | 2.5 ± 2.1 | 3.3 ± 3.1 | 0.006 |
Steroid treatment | 183 (16.7) | 247 (22.1) | 0.001 |
Interval from admission to steroid, days | 2.5 ± 2.7 | 3.1 ± 3.1 | 0.042 |
Antibiotic treatment | 50 (4.6) | 74 (6.6) | 0.036 |
Interval from admission to antibiotics, days | 1.7 ± 2.1 | 4.2 ± 3.7 | <0.001 |
Outcome measures | |||
O2 supplementation via nasal prong | 201 (18.4) | 303 (27.1) | <0.001 |
Interval from admission to nasal prong, days | 17.5 ± 7.4 | 16.1 ± 8.2 | <0.001 |
Composite outcome for progression to severe disease | 44 (4.0) | 90 (8.0) | <0.001 |
Interval from admission to composite outcome, days | 20.3 ± 3.4 | 19.7 ± 4.5 | <0.001 |
O2 supplement via facial mask | 10 (0.9) | 34 (3.0) | <0.001 |
Interval from admission to facial mask, days | 4 (3–5) | 5 (3–7) | 0.002 |
O2 supplement via HFNC | 26 (2.4) | 40 (3.6) | 0.097 |
Interval from admission to HFNC, days | 3 (1–5) | 5 (2–7) | <0.001 |
Referral to tertiary care center | 20 (1.8) | 57 (5.1) | <0.001 |
Interval from admission to referral, days | 4 (2–6) | 5 (3–8) | 0.001 |
Live discharge after recovery without referral | 1075 (98.2) | 1058 (94.5) | <0.001 |
Interval from admission to discharge, days | 10.3 ± 3.7 | 12.3 ± 12.5 | <0.001 |
In-hospital mortality during follow-up period | 0 (0.0) | 4 (0.4) | 0.125 |
Data are expressed as the number (%) of patients, mean ± SD, or median (IQR) unless indicated otherwise.
NA, not applicable; HFNC, high flow nasal cannula; SD, standard deviation; IQR, interquartile range.