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. 2023 May 15;14:1189520. doi: 10.3389/fimmu.2023.1189520

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Copyright © 2023 Zhang, Liu, Pei, Wu, Xie, Liu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Annotation of single-cell data and extraction of Mast cell. (A) Differentially expressed marker genes were used to identify each cell group. (B) Typical marker genes for each cell group. (C) The tSNE plot showed that all the cells in the 12 lung adenocarcinoma samples can be classified into 24 clusters. (D) The tSNE map indicates that lung adenocarcinoma samples can be annotated as 7 cell types in the tumor microenvironment (different colors represent different cell types). (E) AUCell score of model genes in each cell.