Table 1.
Demographic and clinical characteristics of patients at baseline.
Ubiquinol N = 61 | Placebo N = 68 | |
---|---|---|
Age | ||
Mean (SD) | 59.8 (8.5) | 62.0 (8.3) |
Median (min, max) | 61.0 (43, 79) | 61.5 (42, 78) |
Sex | ||
Number (male/female) | 44/17 (72.1%/27.9%) | 38/30 (55.9%/44.1%) |
UMSARS part 2 score | ||
Mean (SD) | 23.2 (8.7) | 23.3 (7.9) |
V393A in COQ2 | ||
Number of carriers | 10 (16.4%) | 11 (16.2%) |
Subtype | ||
Number of MSA-C | 48 (78.7%) | 51 (75.0%) |
Number of MSA-P | 13 (21.3%) | 17 (25.0%) |
Body height (cm) | ||
Mean (SD) | 163.4 (9.2) | 161.3 (9.8) |
Body weight (kg) | ||
Mean (SD) | 65.5 (13.1) | 61.6 (12.1) |
Body mass index | ||
Mean (SD) | 24.5 (4.2) | 23.6 (3.2) |
Past medical history | ||
Present | 30 (49.2%) | 40 (58.8%) |
Absent | 31 (50.8%) | 28 (41.2%) |
Comorbidity | ||
Present | 59 (96.7%) | 61 (89.7%) |
Absent | 2 (3.3%) | 7 (10.3%) |
Disease duration (year) | ||
Mean (SD) | 3.7 (1.8) | 3.8 (1.7) |
Median (min, max) | 3.0 (1, 10) | 3.0 (1, 10) |