Fig. 4.

Liver pathology vs. [U–¹³C₃]glycerol metabolism to glutamate or glycine (A) [U–¹³C₃]glycerol metabolism to glutamate was not significantly changed in the liver with steatosis, inflammation or fibrosis. [¹³C₂]Glu at the x-axis is the sum of [2,3–¹³C₂]glutamate and 4,5–¹³C₂]glutamate. (B) According to the appearance of [U–¹³C₂]glycine, [U–¹³C₃]glycerol metabolism to glycine remained unchanged in the liver with steatosis, inflammation or fibrosis. The data from patient 7 was excluded due to a short duration from [U–¹³C₃]glycerol administration to a liver biopsy.