Figure 5.

Actin reorganization in response to N17Rac microinjection in VEC null and VEC positive EC. VEC positive EC responded to microinjected N17Rac with a strong reduction of actin stress fibers (a). After the same treatment VEC null did not show appreciable modification of actin microfilaments (c). Microinjected cells were TRITC-dextran labeled as shown in b and d. They are indicated by arrowheads in a and c. The effects presented in the figure were observed 1 h after microinjection, but similar responses were already present 30 min after injection (our unpublished data). Bar, 20 μm.