Table 2. This table demonstrates the cellular role present in the pancreatic beta cells involving mitochondrial reactive oxygen species generation with AGE and DAG [3].
ROS (reactive oxygen species) | Function |
NADH (nicotinamide adenine dinucleotide) | Provides electrons for aerobic ATP production |
FADH2 (flavin adenine dinucleotide) | High energy electron carrier, transports electrons produced in glycolysis and Krebs cycle |
AGE | Production of Maillard reaction, proteins or lipids that become glycated after exposure to sugar contributing to development of atherosclerosis |
DAG | Secondary lipid messenger for transducing signals downstream of many receptors for activation, proliferation, migration |