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. 2022 Jul 15;25(3):331–338. doi: 10.4103/aja202242

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Copyright: © The Author(s)(2022)

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Apoptosis-associated protein expression in the testicular tissue from db/m mice and db/db mice treated with dapagliflozin (Dapa) and dapagliflozin + exendin (9–39) (Ex). (a) Representative plots of the expression of the antiapoptotic protein BCL2, the proapoptotic protein BAX and the protein α-tubulin. Quantitative analysis of the expression of (b) the antiapoptotic protein BCL2 and (c) the proapoptotic protein BAX. (d) Representative plots of the expression of the antiapoptotic protein XIAP, the proapoptotic proteins Caspase3, Caspase8 and Caspase9, and the protein α-tubulin. Quantitative analysis of the expression of (e) the antiapoptotic protein XIAP, (f) the proapoptotic protein Caspase3, (g) the proapoptotic protein Caspase8, and (h) the proapoptotic protein Caspase9. n = 5 mice per group in a–c, n = 4 mice per group in d–h. All data are presented as the mean ± standard error of mean. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. BCL2: B-cell lymphoma 2; BAX: BCL2-associated X protein; XIAP: X-linked inhibitor of apoptosis protein.