Figure 1.

Flow diagram of study overview with inclusion and exclusion criteria. Twelve patients met the inclusion criteria and were matched to transmasculine and gender-diverse control subjects (assigned female at birth) who remained on testosterone therapy but did not undergo oophorectomy during the study period. The most common reason for exclusion included no preoophorectomy serum laboratory measurements available in the patient’s chart. EMR: electronic medical record; GAS: gender-affirming surgery.