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Helical repeat proteins for an optimized, synchronized, and regulated expression of transgenes in organelles. The expression of native or designer helical repeat proteins encoded in the nucleus under control of the c6 promoter can be induced specifically by copper depletion. After its translation in the cytosol, the protein is imported into the organelle, where it interacts with BS to regulate the expression of a synthetic operon encoding the proteins X, Y, and Z.
