Additional Table 1.
List of included studies
| Title | Author | Source |
|---|---|---|
| A preliminary evaluation on the efficacy of ozone therapy in the treatment of COVID-19. | Zheng, Zhishui; Dong, Minglin; Hu, Ke | J Med Virol; 92(11): 2348-2350, 2020 11. |
| Blood ozonization in patients with mild to moderate COVID-19 pneumonia: a single centre experience. | Tascini, Carlo; Sermann, Giovanni; Pagotto, Alberto; Sozio, Emanuela; De Carlo, Chiara; Giacinta, Alessandro; Sbrana, Francesco; Ripoli, Andrea; Castaldo, Nadia; Merelli, Maria; Cadeo, Barbara; Macor, Cristiana; De Monte, Amato | Intern Emerg Med; 2021 Feb 03. |
| Case report: recovery of one ICU-acquired COVID-19 patient via ozonated autohemotherapy. | Junping Wu; Cherie S. Tan; Hongzhi Yu, M.M; Youwei Wang; Yutao Tian; Wenwei Shao; Yifei Zhang; Kuo Zhang; Hongxia Shao; Guangjian Ni; Jun Shen; Qi Wu, M.M; Dong Ming. | The Innovation; 2020 |
| Complementary application of the ozonized saline solution in mild and severe patients with pneumonia COVID-19: A non-randomized pilot study | Schwartz, A.; Martínez-Sánchez, G.; de Lucía, A. M.; Viana, S. M.; Constanta, A. M. | J Pharm Pharmacognosy Res; 2021 2(9):126-46 |
| Effect of Rectal Ozone (O3) in Severe COVID-19 Pneumonia: Preliminary Results. | Fernández-Cuadros, Marcos Edgar; Albaladejo-Florín, María Jesús; Álava-Rabasa, Sandra; Usandizaga-Elio, Isabel; Martinez-Quintanilla Jimenez, Dolores; Peña-Lora, Daiana; Neira-Borrajo, Inmaculada; López-Muñoz, María Jesús; Rodríguez-de-Cía, Javier; Pérez-Moro, Olga Susana | SN Compr Clin Med: 1-9, 2020 Aug 03. |
| Oxygen-ozone (O(2)-O(3)) immunoceutical therapy for patients with COVID-19. Preliminary evidence reported. | Franzini, Marianno; Valdenassi, Luigi; Ricevuti, Giovanni; Chirumbolo, Salvatore; Depfenhart, Markus; Bertossi, Dario; Tirelli, Umberto | Int Immunopharmacol; 88: 106879, 2020 Nov. |
| Ozone therapy for patients with COVID-19 pneumonia: Preliminary report of a prospective case-control study. | Hernández, Alberto; Viñals, Montserrat; Pablos, Asunción; Vilás, Francisco; Papadakos, Peter J.; Wijeysundera, Duminda N.; Bergese, Sergio D.; Vives, Marc | Int Immunopharmacol; 88: 106879, 2020 Nov. |
| Potential Role of Oxygen-Ozone Therapy in Treatment of COVID-19 Pneumonia. | Hernández, Alberto; Viñals, Montserrat; Isidoro, Tomas; Vilás, Francisco | Am J Case Rep; 21: e925849, 2020 Aug 17. |
| Safety and efficacy of ozone therapy in mild to moderate COVID-19 patients: A phase 1/11 randomized control trial (SEOT study). | Shah, Mili; Captain, Jignasha; Vaidya, Vidyadhar; Kulkarni, Arvind; Valsangkar, Kedar; Nair, Pradeep M. K.; Ganu, Gayatri | Int Immunopharmacol; 91: 107301, 2021 Feb. |
| Uso de ozonoterapia rectal en paciente anciana con neumonía grave por COVID-19 | Peña-Lora, Daiana Yulissa; Albaladejo-Florín, María Jesús; Fernández-Cuadros, Marcos Edgar | Rev Esp Geriatr Gerontol; 55(6): 362-364, 2020. |
| Utilization of Ozone as a Complementary Therapy for COVID-19 Patients. | Husham A. Razzaq, Mohammad S. Hasan, Muthanna F. Al-Dhalemy, Wurood M. Al-Silaykhee, Hekmat B. Alhmadi, Zaid A. Majeed | Int J Psychosoc Rehab; 24(7):10577-88, 2020. |
| Old Treatment for a New Disease: Can Rectal Ozone Insufflation Be Used for COVID-19 Management? A Case Report. | Hendawy, H.A.; Mosallam, W.; Abuelnaga, M.E.; Sabry, A.M. | SN Compr Clin Med. 3(6):1424-1427, 2021. |
| A pilot study for treatment of COVID-19 patients in moderate stage using intravenous administration of ozonized saline as an adjuvant treatment-registered clinical trial. | Sharma A, Shah M, Lakshmi S, Sane H, Captain J, Gokulchandran N, Khubchandani P, Pradeep MK, Gote P, Tuppekar B, Kulkarni P, Paranjape A, Pradhan R, Varghese R, Kasekar S, Nair V, Khanbande U. | Int Immunopharmacol. 96:107743, 2021. |