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. 2023 May 29;14:3092. doi: 10.1038/s41467-023-38663-7

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© The Author(s) 2023, corrected publication 2023

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Fig. 5 — a UMAP embedding of the adult mouse kidney scRNA-seq combined dataset, with the distribution of wildtype and Fame KO cells. Cell types are indicated. PTc proximal convoluted tubules, PTs proximal straight tubule, PTf female-specific cells, PT1 unidentified subcluster of PT, PT2 unidentified subcluster of PT, GL endo endothelial cells in glomeruli, GL podo podocytes in glomeruli, GL sc putative stem cells, LOH loop of Henle, DCT distal convoluted tubule, CD PC collecting duct principal cells, CD IC/CD Trans collecting duct intercalated cells and transitional cells, VSMC vascular smooth muscle cells, Juxt ldl LOH long descending limb of the loop of Henle in juxtamedullary nephrons, PE parietal epithelium in glomeruli, Fib fibroblasts, RBC red blood cells. b Stacked bar plots of combined dataset illustrating the composition of cell types by genotype. c Violin plots of significantly differentially expressed genes in the PT1 cluster.