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. 2023 Jan 30;162(3):461–469. doi: 10.1007/s11060-023-04250-5

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Fig. 1 — Histology of IDH-mutant gliomas. Astrocytoma, IDH-mutant CNS WHO grade 2 with low cellularity and mild nuclear atypia (a), grade 3 showing increased cellularity and mitotic activity (M, arrows) (b), grade 4 exhibiting microvascular proliferation (c, MP) and palisading necrosis (d, N). Oligodendroglioma, IDH-mutant and 1p/19q-codeleted CNS WHO grade 2 displaying the typical honeycomb appearance (e) and grade 3 showing microvascular proliferation (MP) and increased mitotic activity (M)