Table 3.

Linear regression model of change in pupil size and age, lux^a, and baseline pupil size on the brimonidine treated eye

	Intercept (30 min)		Intercept (120 min)
	Mean	P-value	Mean	p-value
Age	− 0.01	0.06	− 0.008	0.21
Lux	0.003	0.44	0.004	0.51
Baseline	− 0.17	0.008	− 0.233	0.006

This sensitivity analysis shows that the difference in pupil size change from T0 to T30 and T120 in the volunteers compared to the comatose patients was not affected by age or room illuminance. A larger pupil size at T0 resulted in a larger difference at T30 and T120

^aRoom illuminance