Table 3.
Univariate and Multivariable Analysis of Quality of Life Scores and Primary End Point
| Univariate analysis | P value | Multivariable analysis | P value | |
|---|---|---|---|---|
| HR (95% CI) | Adjusted HR (95% CI) | |||
| SF‐36 | ||||
| Physical | 0.98 (0.97–0.99) | 0.008 | 1.00 (0.98–1.01) | 0.715 |
| RLPH | 0.98 (0.97–0.99) | 0.008 | 0.99 (0.97–1.00) | 0.136 |
| RLEP | 1.00 (0.99–1.01) | 0.445 | 1.00 (0.99–1.01) | 0.699 |
| Energy | 0.99 (0.97–1.00) | 0.139 | 1.00 (0.98–1.03) | 0.725 |
| Emotion | 1.01 (0.99–1.03) | 0.418 | 1.02 (1.00–1.04) | 0.103 |
| Social | 1.00 (0.99–1.01) | 0.876 | 1.01 (1.00–1.03) | 0.124 |
| Pain | 0.99 (0.98–1.00) | 0.156 | 1.00 (0.99–1.02) | 0.691 |
| General | 0.97 (0.95–0.99) | 0.002 | 0.99 (0.97–1.01) | 0.195 |
For multivariable analysis, quality of life scores were adjusted for patient characteristics found to be significant and related to mortality (see Table 2); they were history of renal failure, history of pulmonary arterial hypertension, NYHA class III‐IV, and BNP >360 ng/L. BNP indicates brain natriuretic peptide; HR, hazard ratio; NYHA, New York Heart Association; RLEP, role limitations due to emotional problems; RLPH, role limitations due to physical health; and SF‐36, 36‐Item Short Form.