Table 2.
Unadjusted Comparison of Arterial Hemodynamics Between Preeclampsia and Controls
| Variable | Preeclampsia (n=40) mean±SD | Controls (n=40) mean±SD | P value |
|---|---|---|---|
| Aortic stiffness | |||
| cfPWV, m/s | 6.3±1.0 | 5.7±0.7 | 0.001* |
| e‐aPWV (m/s) – median (IQR) | 6.4 (5.9–7.0) | 5.9 (5.6–6.1) | <0.0001‡ |
| EVA, n (%) | 14 (45%) | 3 (18%) | 0.049† |
| Pulsatile arterial load | |||
| Zc, dyne × s × m−5 | 186.0±53.8 | 175.0±4.3.5 | 0.320* |
| Pf, mm Hg | 39±11 | 37±9 | 0.323* |
| PAC (10−6 cm4/dyne) – median (IQR) | 8.9 (6.9–10.4) | 10.0 (8.7–12.0) | 0.032‡ |
| TAC, mL/mm Hg | 1.5±0.5 | 1.7±0.4 | 0.049* |
| Central blood pressure | |||
| Central SBP, mm Hg | 110 (97–122) | 94 (90–100) | <0.0001‡ |
| Central DBP, mm Hg | 62 (58–72) | 54 (52–60) | <0.0001‡ |
| Central PP, mm Hg | 46±14 | 39±8 | 0.010* |
| Steady arterial load | |||
| SVR, dyne×s×cm−5 | 1881.0 (1639.0–2133.0) | 1571.5 (1397.5–1692.5) | <0.0001‡ |
| Arterial wave reflections | |||
| Pb, mm Hg | 13 (10–17) | 11 (10–13) | 0.031‡ |
| AIx, % | 10.1±9.6 | 1.0±8.6 | <0.0001* |
| GRC | 0.35±0.07 | 0.32±0.06 | 0.015* |
AIx indicates augmentation index; cfPWV, carotid‐femoral pulse wave velocity; DBP, diastolic blood pressure; e‐aPWV, estimated aortic pulse wave velocity calculated based on age and mean arterial pressure; EVA, early vascular aging; GRC, global reflection coefficient; IQR, interquartile range; PAC, proximal aortic compliance; Pb, reflected pressure wave amplitude; Pf, forward pressure wave amplitude; PP, pulse pressure; SBP, systolic blood pressure; SVR, systemic vascular resistance; TAC, total arterial compliance; and Zc, aortic characteristic impedance.
*
Comparison made using a t test.
†
Comparison made using a χ2 test.
‡
Comparison made using Wilcoxon rank‐sum test.