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. Author manuscript; available in PMC: 2023 May 30.
Published in final edited form as: Lancet Infect Dis. 2022 Apr 12;22(7):1021–1029. doi: 10.1016/S1473-3099(21)00812-4

Table 3:

Association between MenB-4C vaccination and gonorrhoea or gonorrhoea and chlamydia co-infection compared with chlamydia assuming a duration of vaccine-induced protection of 6 months

Gonorrhoea
Gonorrhoea and chlamydia co-infection
UPR (95% CI) p value APR (95% CI) p value UPR (95% CI) p value APR (95% CI) p value

MenB-4C vaccination status
Complete vaccination* 0.58 (0.48-0.71) <0.0001 0.61 (0.49–0.77) <0.0001 0.92 (0.73–1.16) 0.47 0.87 (0.66–1.13) 0.31
Partial vaccinationt 0.70 (0.62-0.78) <0.0001 0.66 (0.58–0.76) <0.0001 1.10 (0.95–1.26) 0.21 0.97 (0.83–1.15) 0.80
Unvaccinated 1 (ref) .. 1 (ref) .. 1 (ref) .. 1 (ref) ..
Race or ethnicity
Black, non-Hispanic 0.95 (0.88–1.02) 0.26 0.94 (0.88–1.02) 0.17 1.38 (1.22–1.54) <0.0001 1.37 (1.22–1.55) <0.0001
Hispanic 0.68 (0.63–0.74) <0.0001 0.72 (0.67–0.79) <0.0001 0.84 (0.74–0.96) 0.011 0.88 (0.77–1.01) 0.071
Other§ 0.94 (0.84-1.06) 0.46 0.98 (0.87–1.11) 0.79 1.31 (1.08–1.56) 0.0040 1.33 (1.11–1.61) 0.0018
White, non-Hispanic 1 (ref) .. 1 (ref) .. 1 (ref) .. 1 (ref) ..
Gender
Male 2.68 (2.59–2.78) <0.0001 2.69 (2.58–2.80) <0.0001 2.12 (2.01–2.23) <0.0001 2.10 (1.98–2.23) <0.0001
Female 1 (ref) .. 1 (ref) .. 1 (ref) .. 1 (ref) ..
Jurisdiction
New York City, NY, USA 0.74 (0.71-0.77) <0.0001 1.01 (0.97–1.06) 0.41 0.71 (0.68–0.75) <0.0001 0.99 (0.93–1.05) 0.78
Philadelphia, PA, USA 1 (ref) .. 1 (ref) .. 1 (ref) .. 1 (ref) ..

APR=adjusted prevalence ratio. UPR=unadjusted prevalence ratio. STI=sexually transmitted infection.

*

Receipt of two doses of MenB-4C doses separated by 30–180 days.

Receipt of one MenB-4C dose.

Never vaccinated against Neisseria meningitidis serogroup B with MenB-4C or MenB-FHbp (ie, MenB vaccine naive or STI occurred before first MenB-4C vaccine dose).

§

Asian, American Indian, Native Hawaiian or Pacific Islander, other race, or two or more races.