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. 2022 Dec 7;35(2):152–157. doi: 10.4103/tcmj.tcmj_223_22

Table 3.

Genotyping and allele frequency of interleukin-12A- rs568408 in coronavirus disease 2019 patients and control

Variables Patients (n=125), n (%) Control (n=60), n (%) OR (95% CI) P
IL-12A rs568408
 GG 65 (52) 45 (75) 1 1
 AA 15 (12) 2 (3.3) 5.19 (1.13-23.82) 0.034
 AG 45 (36) 13 (21.7) 2.39 (1.16-4.94) 0.018
 AA + AG 60 (48) 15 (25) 2.76 (1.40-5.47) 0.003
 P trend 0.006
Allele frequency
 G 175 (70) 103 (85.83) 0.001
 A 75 (30) 17 (14.17) 2.59 (1.45-4.63)
Recessive model
 GG + AG 110 (88) 58 (96.7) 0.056
 AA 15 (12) 2 (3.3) 3.95 (0.87-17.88)
Additive model
 GG 65 (52) 45 (75) 0.021
 AA 15 (12) 2 (3.3) 5.19 (1.13-23.82)
Dominant model
 GG 65 (52) 45 (75) 0.003
 AA + AG 60 (48) 15 (25) 2.67 (1.40-5.47)

OR: Odds ratio, CI: Confidence interval, IL: Interleukin