Table 3.
Variables | Patients (n=125), n (%) | Control (n=60), n (%) | OR (95% CI) | P |
---|---|---|---|---|
IL-12A rs568408 | ||||
GG | 65 (52) | 45 (75) | 1 | 1 |
AA | 15 (12) | 2 (3.3) | 5.19 (1.13-23.82) | 0.034 |
AG | 45 (36) | 13 (21.7) | 2.39 (1.16-4.94) | 0.018 |
AA + AG | 60 (48) | 15 (25) | 2.76 (1.40-5.47) | 0.003 |
P trend | 0.006 | |||
Allele frequency | ||||
G | 175 (70) | 103 (85.83) | 0.001 | |
A | 75 (30) | 17 (14.17) | 2.59 (1.45-4.63) | |
Recessive model | ||||
GG + AG | 110 (88) | 58 (96.7) | 0.056 | |
AA | 15 (12) | 2 (3.3) | 3.95 (0.87-17.88) | |
Additive model | ||||
GG | 65 (52) | 45 (75) | 0.021 | |
AA | 15 (12) | 2 (3.3) | 5.19 (1.13-23.82) | |
Dominant model | ||||
GG | 65 (52) | 45 (75) | 0.003 | |
AA + AG | 60 (48) | 15 (25) | 2.67 (1.40-5.47) |
OR: Odds ratio, CI: Confidence interval, IL: Interleukin