Table 6.

Consensus values calculated from the score energies of the Linalool derivatives under study and their Alzheimer's and Parkinson's disease target enzymes.

	Linalool Derivatives
ID	Parkinson’s Disease Targets						Alzheimer’s Disease Targets
	α-Sinuclein	Adenosin A2A	COMT	MAO	D1	D2	AChE	BACE	GSK3	TACE
L1 Linalool	0.6982	0.5122	0.7371	0.5515	0.5352	0.5348	0.3884	0.6826	0.5088	0.5223
L2 Linalyl	0.8525	0.6915	0.9459	0.6701	0.7950	0.6706	0.4968	0.8919	0.6519	0.6514
L3 8-hydroxylinalyl acetate	0.8164	0.8706	0.7698	0.6997	0.6847	0.6711	0.4965	0.9615	0.4677	0.6358
L4 8-oxolinalyl acetate	0.8421	0.7228	0.8037	0.7334	0.6465	0.6804	0.4672	0.8779	0.5782	0.6615
L5 8-carboxylinalyl acetate	1	0.8108	1	0.7250	0.6873	0.6261	0.4815	0.9456	0.3289	0.7393
L6 8-oxo-dihydrolinalool	0.7350	0.6019	0.7679	0.6011	0.5844	0.5740	0.4016	0.8214	0.6054	0.5580
L7 8-oxo-dihydrolinalool	0.6384	0.5901	0.7560	0.5857	0.5929	0.5667	0.4282	0.7627	0.2970	0.5540
L8 8-oxolinalool	0.7212	0.5947	0.6594	0.5845	0.5707	0.5607	0.3800	0.7277	0.5610	0.5597
L9 8-carboxylinalool	0.8377	0.5146	0.9325	0.6282	0.6559	0.5390	0.4186	0.6873	0.3308	0.5518
L10 Tetrahydrolinalool	0.6532	0.5331	0.7345	0.5608	0.4906	0.5363	0.3769	0.6300	0.5164	0.5162
Positive Control	0.8199	0.5	0.8206	0.5356	0.6564	0.6586	0.6660	-	-	-
PDB Ligand	-	0.9386	0.9268	0.5	0.7246	1	1	0.9684	1	1

Note: The molecule with the highest probability is in bold. Compounds with a higher probability than the ligand are in yellow.