Fig. 8.

Probability of a TAD to be near NE is largely determined by the linear density of L-TADs surrounding this TAD. Shown are the probabilities of TADs/L-TADs to be found within 0.4 $\mu$m layer adjacent to the NE (upper trace), $p_{\mathit{NE}}$, and the linear L-TAD density, $f_L$, along the chromosome chain (lower trace). For visual clarity, only a fraction of 2 L chromosome is shown