Table 5.

Cholera vaccination during pregnancy results.

Author	Country	Effect of cholera vaccine on pregnancy
Hashim et al. [14]	Korea	Both groups had approximately the same probability of spontaneous abortions, fetus abnormalities, or deaths
Ciglenecki et al. [18]	Haiti	Women who were previously exposed to cholera had a higher chance of pregnancy loss and fetal abnormality compared to healthy women
Grout et al. [20]	USA	(i) 3.7% (95% CI 2.7–4.8) of miscarriages were observed among vaccinated women compared to 2.6% among nonvaccinated ones (ii) Vaccinated women were at lower risk of malformation frequency 0.6% (0.1-1.0) compared to nonvaccinated women 1.2% (0.0-2.5) (iii) Even if there was a correlation between the exposure of the vaccine and the risk of miscarriage or fetal deformity, it is negligible (iv) The OCV is safe for pregnant women and does not offer any risk to the fetus (v) A negative relationship was seen between the Shanchol vaccine exposure and fetal complications
Ali et al. [13]	USA	Compared to 835 nonvaccinated women, 835 vaccinated women were at an equal risk of stillbirth, spontaneous abortion, birth defects, or fetal mortality
Khan et al. [12]	Bangladesh	There is no increased risk on the fetuses of OCV-exposed pregnant women
WHO [1]	Worldwide	Vaccinating all pregnant women against the cholera vaccine is effective and safe