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. 2023 May 22;2023:7423661. doi: 10.1155/2023/7423661

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Copyright © 2023 Jiaxin He et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of AS-IV (astragaloside IV) on renal function in DN (diabetic nephropathy) rats. (a–c) The effect of AS-IV on blood sugar and blood lipid levels of DN rats. Scale bar: 25 μm. (d) The effect of AS-IV on UACR (urine albumin creatinine ratio), BUN (blood urea nitrogen), and SCr (serum creatinine), biochemical markers reflecting renal function. (e) The effects of AS-IV on morphology as observed in electron microscopy (8,000x magnification, n = 5). GBM (glomerular basement membrane) is depicted in the yellow box. Scale bar: 0.2 μm. Values are presented as mean ± SD (n = 8, ^∗∗P < 0.01).