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. 2023 May 22;2023:7423661. doi: 10.1155/2023/7423661

Figure 3.

Figure 3

AS-IV upregulates klotho in cultured podocytes exposed to high glucose. (a) The effect of AS-IV on cell viability in podocytes exposed to high glucose. (b) AS-IV treatment increases klotho and nephrin expression in podocytes exposed to high glucose via immunofluorescence staining (630x magnification, n = 3). Scale bar: 50 μm. (c) AS-IV treatment ameliorates morphological changes in podocytes exposed to high glucose. Scale bar: 50 μm. (d) AS-IV treatment increases klotho and nephrin expression in podocytes exposed to high glucose via western blot assay. Values are presented as mean ± SD (n = 3, ∗P < 0.05 and ∗∗P < 0.01).