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AS-IV inhibits pyroptosis in DN glomeruli. (a) The effect of AS-IV on DNA (deoxyribonucleic acid) fragmentation in DN glomeruli as evidenced by TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling) staining (200x magnification, n = 3). Scale bar: 20 μm. (b) The effect of AS-IV on pyroptosis-related parameters in DN kidneys. Values are presented as mean ± SD (n = 3, ∗P < 0.05 and ∗∗P < 0.01).
