Table 3.
Subgroup analysis of the association between circulating TMAO concentrations and all-cause mortality in dialysis patients.
| Subgroup | Studies | RR | 95%CI | Z | P | Heterogeneity |
|
|---|---|---|---|---|---|---|---|
| I2, % | * P | ||||||
| Age | |||||||
| <60 | 6 [13,35,47,36] | 1.29 | 0.93,1.80 | 1.52 | 0.129 | 79.0 | 0.000 |
| >60 | 2 [42,48] | 0.99 | 0.94,1.04 | 0.34 | 0.733 | 0.000 | 0.603 |
| Race | |||||||
| Including blacks | 4 [42,36,37,48] | 0.98 | 0.94,1.03 | 0.61 | 0.542 | 0.000 | 0.649 |
| Non-blacks | 4 [13,35,47,36] | 1.62 | 1.19,2.22 | 3.05 | 0.002 | 56.7 | 0.074 |
| Dialysis modality | |||||||
| PD | 2 [35,47] | 1.32 | 0.98,1.79 | 1.82 | 0.069 | 0.000 | 0.928 |
| HD | 6 [13,42,36,37,48] | 1.19 | 0.90,1.55 | 1.23 | 0.219 | 82.1 | 0.000 |
*For heterogeneity among subgroups.
RR: relative risk; CI: confidence interval.