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. 2023 May 27;15(1):2205540. doi: 10.1080/19420862.2023.2205540

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© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 13. — Viscosity reducing agents used in formulations of approved HCAPs (n = 23).

The number of products that contain a viscosity reducing agent (n) in parenthesis.

Among the reviewed 46 HCAPs, there are 23 instances wherein viscosity reducing agents (i.e., arginine and its hydrochloride salt, proline, lysine hydrochloride, glycine, and sodium chloride) were used.