TABLE 2:
Current and completed clinical trials examining radiosensitizers in HNC
NCT no. | Phase | Intervention | Disease | Study status |
---|---|---|---|---|
NCT00001442 31 | I | Paclitaxel, radiotherapy | Head and neck squamous cell carcinoma | Completed |
NCT00410826 41 | III | Erlotinib hydrochloride, cisplatin, 3-dimensional conformal radiotherapy and intensity-modulated radiotherapy | Stage III and IV squamous cell carcinoma of hypopharynx, larynx, lip and oral cavity, nasopharynx and oropharynx | Completed |
NCT04722523 49 | I | Cisplatin, carboplatin, docetaxel, cetuximab, cemiplimab, surgical resection, radiotherapy | Head and neck squamous cell carcinoma | Recruiting |
NCT01384799 68 | I | Cisplatin, CUDC-101, radiotherapy | Locally advanced head and neck squamous cell carcinoma | Completed |
NCT01880359 72 | III | Placebo, cisplatin, nimorazole | Locally advanced, HPV negative head and neck squamous cell carcinoma | Active, not recruiting |
NCT02229656 66 | I | Olaparib, radiotherapy | Stage II and III laryngeal cancer, head and neck squamous cell carcinoma | Active, not recruiting |
NCT01507467 74 | III | Nimorazole, accelerated fractionated radiotherapy | Head and neck squamous cell carcinoma | Terminated |