Table 6.

Multivariable analysis^a for a single procedure outcome of freedom of all atrial arrhythmias at 12 months

Variable or pairwise comparison, where applicable	Odds ratio (95% CI)	P-valueb
Treatment prior to enrollment:	—	0.0005
First retreatment following a de novo PVI-only procedure vs. first Retreatment following a de novo PVI + Procedure	6.55 (2.18, 19.70)	0.0008*
First retreatment following a de novo PVI-only procedure vs. second retreatment	2.86 (1.03, 7.94)	0.0434*
CHADS-VASC (1-unit increase)	0.63 (0.43, 0.92)	0.0163

PVI, pulmonary vein isolation.

^aVariables with univariate P ≤ 0.20 were considered for multivariable model. Stepwise selection was used to determine variables in final model.

^bBased on overall type 3 P-values or pairwise tests (denoted by *, no adjustments for multiple comparisons were made).