FIGURE 3.

Central corneal nerve bed coverage in naïve, vehicle-, and CMP 03A-treated mice. Representative confocal images of βIII-tubulin-stained nerve fibers in the whole cornea with higher magnification images of the central sub-basal plexus and epithelial terminals. The dashed boxes indicate central swirl location. (A) Naïve animals have an intact central nerve fiber swirl and robust sub-basal plexus and nerve terminal coverage. (B) Desiccation with vehicle treatment only led to reduced sub-basal plexus and epithelial terminal coverage. (C) CMP 03A-treated mice did not exhibit a reduced nerve coverage at the sub-basal or terminal epithelial plexus.