TABLE 2.

Risk of bias of the included studies.

Study	A	B	C	D	E	F	G	H	I	J	Total
Ma et al., 2017	√		√			√					3
Dai et al., 2013	√		√			√					3
Tang et al., 2017	√	√	√			√			√	√	6
Zheng et al., 2010	√		√			√					3
Zhang and Zhang. 2010	√		√			√					3
Han et al., 2016	√		√			√				√	4
Wu and He. 2012	√		√			√				√	4
Zhou and Yang. 2012	√		√			√				√	4
Han. 2011	√		√			√					3
Li et al., 2016a	√	√	√			√			√	√	6
Long et al., 2015	√	√	√			√			√	√	6
Pan et al., 2017	√	√	√			√			√	√	6
Hu et al., 2015	√	√	√			√			√	√	6
Wei et al., 2014	√	√	√			√			√		5
Li et al., 2010	√		√			√				√	4
Fu et al., 2007	√	√	√			√			√	√	6
Zhang et al., 2010	√	√	√			√	√		√	√	7
Li et al., 2016b	√	√	√			√			√	√	6
Wang 2021	√		√			√					3
Li et al., 2017	√		√			√				√	4
Shen et al., 2018	√	√	√			√			√	√	6
Tao et al., 1996	√		√			√					3
Wang et al., 2016	√		√			√				√	4
Ai 2013	√		√			√					3
Wang et al., 2012	√		√			√				√	4
Lin et al., 2013	√		√			√				√	4
Wang et al., 2007	√		√			√					3
Liu et al., 2017	√	√	√			√			√	√	6

Note: Studies fulfilling the criteria of: A: peer reviewed publication; B: control of temperature; C: random allocation to treatment or control; D: blinded induction of model; E: blinded assessment of outcome; F: use of anesthetic without significant intrinsic cardioprotective activity; G: appropriate animal model (aged, diabetic, or hypertensive); H: sample size calculation; I: compliance with animal welfare regulations; J: statement of potential conflict of interests. Compliant item was given one point using a tick to indicate.