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. 2023 May 30;11(6):e50. doi: 10.1016/S2213-2600(23)00148-0

Table.

Day 45 and day 180 outcomes for the anti-coronavirus therapy trials

Inpatient trial (n=2749)
Outpatient trial (n=3917)
Colchicine vs control Rivaroxaban plus aspirin vs control Colchicine vs control Aspirin vs control
Primary outcome Ventilation, high-flow oxygen, or death Major thrombosis, ventilation, high-flow oxygen, or death Hospitalisation or death Major thrombosis, hospitalisation, or death
Day 45
Patients with events 725 (27·8%) 582 (27·5%) 131 (3·4%) 132 (3·4%)
HR 1·04 (0·90–1·21) 0·92 (0·78–1·09) 1·02 (0·72–1·43) 0·80 (0·57–1·13)
Day 180*
Patients with events 734 (28·1%) 589 (27·8%) 145 (3·7%) 146 (3·8%)
HR 1·06 (0·92–1·23) 0·93 (0·79–1·10) 1·10 (0·80–1·53) 0·84 (0·61–1·17)
Patients with first events between day 45 and day 180* 3 per 1000 3 per 1000 3 per 1000 4 per 1000

Data are n (%) or HR (95% CI). HR=hazard ratio.

*

A total of 78 patients were lost to follow-up or withdrew consent prior to the final visit.

1981 patients participated in both randomisations, 630 participated only in the colchicine vs control randomisation and 130 participated only in the rivaroxaban plus aspirin vs control randomisation.