Table 3.
Results of the general linear model repeated-measures analysis.
| Source | Type III Sum of Squares | df | Mean Square | F | p-value |
|---|---|---|---|---|---|
| Mini-Mental State Examination (MMSE) | |||||
| Tests of Within-Subjects Effects | |||||
| week | 365.08 | 1.744 | 209.392 | 123.62 | <0.001 |
| week * treatment | 32.49 | 1.744 | 18.637 | 11.00 | <0.001 |
| Error (week) | 141.76 | 83.689 | 1.694 | ||
| Tests of Between-Subjects Effects | |||||
| Intercept | 74,861.34 | 1 | 74,861.340 | 10,707.22 | <0.001 |
| treatment | 62.73 | 1 | 62.727 | 8.97 | 0.004 |
| Error | 335.60 | 48 | 6.992 | ||
| Montreal Cognitive Assessment (MoCA) | |||||
| Tests of Within-Subjects Effects | |||||
| week | 472.09 | 2 | 236.047 | 179.09 | <0.001 |
| week * treatment | 54.04 | 2 | 27.02 | 20.5 | <0.001 |
| Error (week) | 126.53 | 96 | 1.318 | ||
| Tests of Between-Subjects Effects | |||||
| Intercept | 75,622.83 | 1 | 75,622.827 | 14,569.31 | <0.001 |
| treatment | 69.36 | 1 | 69.360 | 13.36 | 0.001 |
| Error | 249.15 | 48 | 5.191 | ||
| Hamilton Depression Rating Scale (HAM-D) | |||||
| Tests of Within-Subjects Effects | |||||
| week | 76.81 | 1.517 | 50.647 | 65.28 | <0.001 |
| week * treatment | 6 | 1.517 | 3.983 | 5.13 | 0.014 |
| Error (week) | 56.48 | 72.798 | 0.776 | ||
| Tests of Between-Subjects Effects | |||||
| Intercept | 17,908.81 | 1 | 17,908.807 | 2552.32 | <0.001 |
| treatment | 0.06 | 1 | 0.060 | 0.01 | 0.927 |
| Error | 336.80 | 48 | 7.017 | ||
| Hamilton Anxiety Rating Scale (HAM-A) | |||||
| Tests of Within-Subjects Effects | |||||
| week | 6.413 | 1.374 | 4.666 | 12.152 | <0.001 |
| week * treatment | 2.253 | 1.374 | 1.640 | 4.269 | 0.031 |
| Error (week) | 25.333 | 65.971 | 0.384 | ||
| Tests of Between-Subjects Effects | |||||
| Intercept | 15,100.17 | 1 | 15,100.17 | 4949.973 | <0.001 |
| treatment | 6.407 | 1 | 6.407 | 2.100 | 0.154 |
| Error | 146.427 | 48 | 3.051 | ||
p-value of <0.05 was considered statistically significant. (Shown in bold).