Figure 3.

Determinants of change in bioprosthetic valve function. Forest plots of unstandardized coefficients (95% confidence intervals) from a multivariable linear regression analysis predicting change in bioprosthetic valve function (annualized change in peak velocity) during follow-up. When examining all relevant baseline characteristics, 18F-sodium fluoride uptake was the only independent predictor of hemodynamic deterioration in valve function when serum Lp(a) concentration was used both as (A) a continuous variable and (B) as a dichotomous variable (either in the highest tertile or not). 18F-NaF, 18F-sodium fluoride; CI, confidence interval; CT, computed tomography; LDL-C, low-density lipoprotein cholesterol; Lp(a), lipoprotein(a).