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Figure 10. Co-expression analysis. (a) When the soft domain value was 5, R^2 > 0.8, the data was in line with the power-law distribution, and the trend of the graph was flat, which was suitable for subsequent analysis. (b) WGCNA showed that melanoma patients correspond to different modules. (c) Brown and Red modules were highly expressed in IS2. (d) The number of genes in the Brown module was the largest, with 886 co-expressed immune-related genes, while the red module had only 194 immune-related genes.