TABLE 2.
Number and percentage of enrolled animals having at least 1 adverse event, by VeDDRA preferred term.
| VeDDRA preferred term | n | % |
|---|---|---|
| Emesis | 42 | 50 |
| Diarrhea | 32 | 38 |
| Anorexia | 31 | 37 |
| Lethargy | 17 | 20 |
| Dehydration | 16 | 19 |
| Elevated pancreatic enzymes | 15 | 18 |
| Weight loss | 13 | 16 |
| Increased blood urea nitrogen or creatinine | 12 | 14 |
| Diabetes mellitus a | 10 | 12 |
| Urinary tract infection b | 10 | 12 |
| Elevated liver enzymes | 8 | 10 |
| Elevated symmetrical dimethylarginine | 6 | 7 |
| Hypokalaemia | 6 | 7 |
| Haematuria | 5 | 6 |
| Otitis externa | 5 | 6 |
| Bacterial skin infection | 4 | 5 |
| Elevated aspartate aminotransferase | 4 | 5 |
| Hypercalcaemic condition | 4 | 5 |
| Hypochloraemia | 4 | 5 |
| Hypoglycaemia | 4 | 5 |
| Inappropriate urination | 4 | 5 |
| Myopathy | 4 | 5 |
| Proteinuria | 4 | 5 |
Note: Each affected cat counted once for a given term over the 180 day course of the study. Events were classified by investigators using the Veterinary Dictionary for Drug Regulatory Activities (VeDDRA).
a
Indicates an investigator assessment of poor glycemic control.
b
All urinary tract infections were of bacterial origin.