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. 2022 Dec 16;14(2):238–255. doi: 10.1016/j.advnut.2022.10.007

TABLE 1.

Sources of carotenoid production by microorganisms, and their delivery mechanisms. DCW = dry cell weight.

Delivery to gut Carotenoid Amount Source Genetically modified organism Reference
Probiotic β-carotene 37 μg/g Saccharomyces boulardii Yes [117]
Probiotic lycopene 40.8 mg/mL Bacillus indicus No [28]
Probiotic lycopenoate 23.6 mg/mL Bacillus indicus No [28]
Probiotic lycopene 1.09 mg/L Lactococcus lactis Yes [177]
Supplement β-carotene 7 mg/L Corynebacterium glutamicum No [178]
Supplement β-carotene 6500 mg/L (90 mg/g) Saccharomyces cerevisiae Yes [179]
Supplement β-carotene 4000 mg/L Saccharomyces cerevisiae Yes [180]
Supplement β-carotene 2370 mg/L (73.3 mg/g) Saccharomyces cerevisiae Yes [181]
Supplement β-carotene 2100 mg/L Saccharomyces cerevisiae Yes [182]
Supplement β-carotene 704.1 mg/L Blakeslea trispora No [183]
Supplement β-carotene 44.2 mg/g Saccharomyces cerevisiae Yes [184]
Supplement lycopene 2300 mg/L Saccharomyces cerevisiae Yes [185]
Supplement lycopene 500 mg/g DCW Escherichia coli Yes [186]
Supplement lycopene 256 mg/L Blakeslea trispora No [187]
Supplement lycopene 220 mg/L Escherichia coli Yes [115]
Supplement lycopene 56 mg/g DCW Saccharomyces cerevisiae Yes [188]
Supplement lycopene 10 mg/g DCW Rhodobacter sphaeroides Yes [189]
Supplement astaxanthin 385.0 mg/L (7.0 mg/g) Escherichia coli Yes [190]
Supplement astaxanthin 320 mg/L Escherichia coli Yes [191]
Supplement astaxanthin 218 mg/L Saccharomyces cerevisiae Yes [192]
Supplement astaxanthin 1.7 mg/g Corynebacterium glutamicum No [193]
Supplement zeaxanthin 0.5 mg/g DCW Xanthophyllomyces dendrorhous Yes [194]