Table 2.

Major outcomes of the two groups of patients

	Eradication rate
	HDDT (n = 110)	HT (n = 117)	P-value
Intention to treat	94/122 (77.0%)	114/121 (94.2%)	< 0.001
Per protocol	94/110 (85.5%)	114/117 (97.4%)	0.001
Compliance	110 (100%)	117 (100%)	–

HDDT: high-dose dual therapy (rabeprazole 20 mg and amoxicillin 750 mg q.i.d for 14 days); HT: hybrid therapy (rabeprazole 20 mg and amoxicillin 1 g b.i.d. for 7 days, followed by rabeprazole 20 mg, amoxicillin 1 g, clarithromycin 500 mg and metronidazole 500 mg b.i.d. for 7 days)