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. 2023 May 30;13:8747. doi: 10.1038/s41598-023-35759-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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A case of retinal pigment epithelial (RPE) tear in 77-year-old male patient with polypoidal choroidal vasculopathy. (A) Fundus photography revealed a haemorrhagic pigment epithelial detachment (PED) with subretinal fluid (SRF) and subretinal haemorrhage at the fovea. (B) Fundus autofluorescence (FAF) revealed no RPE tear at baseline (C) Optical coherence tomography (OCT) revealed the large haemorrhagic PED with SRF. (D) Fundus photography at 1 months after the third injection of faricimab revealed that RPE tear developed at the inferior of the PED. (E) FAF identified hemispherical RPE defect at the inferior part of the PED. (F) OCT revealed RPE defect at the inferior part of the pre-existing PED.SRF was completely absorbed. Regardless of the RPE tear development, visual acuity improved from 20/125 to 20/40.