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. 2022 Dec 6;30(6):1841–1853. doi: 10.1007/s43032-022-01130-7

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Fig. 7 — A brief overview of the roles of CR-DEGs in cuproptosis. Gray arrows, intracellular transport processes of copper ion; gray circles, copper ion; black arrows, abbreviated metabolic processes; green boxes, lipoyl-related enzyme complexes; blue boxes, important components of lipoyl-related enzyme complexes; red boxes, enzymes involving in lipoylation; orange circles, lipoyl group. BCAA branched-chain amino acids, BCKDC branched-chain ketoacid dehydrogenase complex, ɑ-KGDH alpha-ketoglutarate dehydrogenase complex, PDHC pyruvate dehydrogenase complex