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. 2023 May 17;11:1170025. doi: 10.3389/fped.2023.1170025

Table 5.

Factors related to the occurrence of at least one side effects.

Crude OR (IC 95%) p-value Adjusted OR (IC 95%) p-value
Leuprolide treatment 0.80 (0.37–1.71) 0.558 1.79 (0.74–4.36) 0.199
Days treatment 1.00 (1.00–1.00) 0.069 1.00 (1.00–1.00) 0.113
Weight (kg) 1.01 (0.95–1.08) 0.772
Height (cm) 0.97 (0.92–1.02) 0.223
Chronological age 0.84 (0.51–1.51) 0.517
Initial bone age 0.67 (0.46–0.98) 0.038 0.67 (0.46–0.98) 0.038
Hormones
 FSH (mUI/ml) 1.06 (0.87–1.29) 0.566
 LH (mUI/ml) 0.83 (0.60–1.14) 0.246
 FSH peak (mUI/ml) 0.99 (0.92–1.07) 0.881
 LH peak (mUI/ml) 0.99 (0.97–1.01) 0.387
 E2 (pg/ml) 1.01 (0.99–1.03) 0.462
 SMC (ng/ml) 1.00 (0.99–1.00) 0.306
Longitudinal diameter (mm) 0.98 (0.93–1.03) 0.376
Uterine body/cervix (mm) 1.38 (0.67–2.81) 0.383
Endometrial (mm) 1.58 (0.70–3.53) 0.268
Ovarian volume (cc) 1.12 (0.93–1.37) 0.238