Table 1.
Baseline characteristics of patients stratified by AISI levels.
| Characteristics | Overall (N = 18,532) | Q1 (N = 4,635) | Q2 (N = 4,632) | Q3 (N = 4,632) | Q4 (N = 4,633) | P-value |
|---|---|---|---|---|---|---|
| Demographic characteristics | ||||||
| Age, years | 55.3 ± 0.2 | 55.0 ± 0.4 | 55.1 ± 0.3 | 55.1 ± 0.3 | 55.8 ± 0.4 | 0.236 |
| Female, n (%) | 9,430 (50.9) | 2,439 (52.0) | 2,378 (50.1) | 2,348 (51.1) | 2,265 (49.2) | 0.228 |
| BMI, kg/m2 | 30.96 ± 0.08 | 30.02 ± 0.13 | 30.59 ± 0.14 | 31.42 ± 0.16 | 31.58 ± 0.17 | <0.001 |
| Race, n (%) | <0.001 | |||||
| Mexican American | 2,943 (15.9) | 644 (6.5) | 777 (6.3) | 814 (6.7) | 708 (5.7) | |
| Non-Hispanic Black | 4,837 (26.1) | 1,962 (26.6) | 1,189 (14.0) | 957 (10.8) | 729 (7.8) | |
| Non-Hispanic White | 7,832 (42.3) | 1,203 (53.0) | 1,872 (67.1) | 2,175 (72.3) | 2,582 (77.1) | |
| Other Hispanic | 1,442 (7.8) | 359 (5.4) | 391 (5.1) | 370 (5.0) | 322 (4.1) | |
| Other Race | 1,478 (8.0) | 467 (8.5) | 403 (7.4) | 316 (5.3) | 292 (5.2) | |
| Smoking, n (%) | 8,961 (48.4) | 2,037 (45.1) | 2,125 (46.2) | 2,283 (49.5) | 2,516 (54.5) | <0.001 |
| Drinking, n (%) | 10,094 (54.5) | 2,455 (60.8) | 2,556 (63.1) | 2,581 (63.2) | 2,502 (60.7) | 0.326 |
| Medical history | ||||||
| DM, n (%) | 5,372 (29.0) | 1,319 (22.8) | 1,300 (21.2) | 1,348 (24.0) | 1,405 (25.1) | <0.001 |
| CKD, n (%) | 5,439 (30.2) | 1,141 (20.6) | 1,243 (23.5) | 1,375 (23.3) | 1,680 (29.9) | <0.001 |
| CHD, n (%) | 1,310 (7.1) | 264 (5.6) | 329 (6.8) | 322 (6.0) | 395 (7.5) | 0.006 |
| CHF, n (%) | 1,092 (5.9) | 211 (3.6) | 222 (3.5) | 275 (4.6) | 384 (6.1) | <0.001 |
| Stroke, n (%) | 1,269 (6.8) | 282 (5.5) | 279 (4.6) | 295 (5.0) | 413 (7.0) | <0.001 |
| Laboratory examination | ||||||
| WBC, 109/l | 7.44 ± 0.03 | 5.83 ± 0.04 | 6.77 ± 0.03 | 7.62 ± 0.03 | 9.13 ± 0.04 | <0.001 |
| NEU, 109/l | 4.45 ± 0.02 | 2.91 ± 0.02 | 3.83 ± 0.02 | 4.60 ± 0.02 | 6.07 ± 0.03 | <0.001 |
| MONO, 109/l | 0.50 ± 0.00 | 0.44 ± 0.01 | 0.53 ± 0.00 | 0.60 ± 0.00 | 0.74 ± 0.00 | <0.001 |
| LYM, 109/l | 2.14 ± 0.01 | 2.26 ± 0.03 | 2.16 ± 0.02 | 2.15 ± 0.02 | 2.03 ± 0.01 | <0.001 |
| HBG, g/l | 14.29 ± 0.03 | 14.11 ± 0.04 | 14.36 ± 0.04 | 14.36 ± 0.04 | 14.29 ± 0.04 | <0.001 |
| PLT, 109/l | 254.20 ± 0.93 | 212.54 ± 1.29 | 236.98 ± 1.20 | 260.67 ± 1.31 | 295.88 ± 1.78 | <0.001 |
| Cr, umol/l | 82.85 ± 0.45 | 81.75 ± 0.64 | 81.12 ± 0.56 | 81.47 ± 0.60 | 86.61 ± 1.10 | <0.001 |
| SBP, mmHg | 134.26 ± 0.24 | 134.53 ± 0.41 | 134.23 ± 0.39 | 134.16 ± 0.44 | 134.17 ± 0.39 | 0.859 |
| DBP, mmHg | 74.88 ± 0.21 | 75.23 ± 0.34 | 75.50 ± 0.32 | 74.83 ± 0.30 | 74.08 ± 0.32 | <0.001 |
| Medicine | ||||||
| Antihypertensive drugs, n (%) | 12,477 (84.1) | 3,092 (80.3) | 3,091 (79.8) | 3,081 (81.8) | 3,213 (84.4) | 0.001 |
| Events | ||||||
| Cardiovascular death | 1,308(7.1) | 244(4.5) | 296(4.9) | 324(5.0) | 444(7.3) | <0.001 |
Values are, n (%) or mean ± SD.
BMI, body mass index; DM, diabetes mellitus; CKD, chronic kidney disease; CHD, coronary heart disease; CHF, congestive heart failure; WBC, white blood cell; NEU, neutrophil; MONO, monocyte; LYM, lymphocyte; HGB; hemoglobin; PLT, platelet; Cr, creatinine; SBP, systolic blood pressure; DBP, diastolic blood pressure.