Table 1.
Expression of RAS and IFN-γ pathway specific molecules as analyzed by IPA (Qiagen) in the lungs of aged hAT1R TG mice post-Francisella tularensis LVS infection.
A | B | C | ||||||
---|---|---|---|---|---|---|---|---|
Pro-inflammatory cytokines | RAS pathway molecules | IFN-γ signaling molecules | Gene symbol | Expr log ratio | Gene symbol | Expr log ratio | Gene symbol | Expr log ratio |
Il17ra | 0.598 | Agtr1 | −1.657 | Bak1 | 2.325 | |||
Il17a | 6.355 | Ccl2 | 2.141 | Bax | 0.997 | |||
Il6 | 4.792 | Nfkb | 1.190 | Ifit1 | 2.261 | |||
Il1rl1 | 2.191 | P38 Mapk | 2.580 | Ifit3 | 3.419 | |||
Il1b | 0.654 | Pi3K | 1.540 | Ifitm3 | 2.018 | |||
Il1a | 2.797 | Ptpn6 | 1.191 | Ifng | 6.046 | |||
Ifng | 6.046 | Ras | 2.900 | Irf1 | 2.586 | |||
Ifngr2 | 0.259 | Stat1 | 2.948 | Irf9 | 1.116 | |||
Il1r2 | 3.473 | Stat3 | 0.919 | Isg15 | 3.977 | |||
Tnf | 2.915 | Tnf | 2.915 | Oas1 | 3.218 | |||
Tnfrsf12a | 1.611 | Psmb8 | 2.810 | |||||
Tnfrsf21 | 0.960 | Ptpn2 | 1.320 | |||||
Socs1 | 4.046 | |||||||
Stat1 | 2.948 | |||||||
Stat2 | 2.304 | |||||||
Tap1 | 3.503 |