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. 2023 May 17;14:1108097. doi: 10.3389/fendo.2023.1108097

Table 2.

Baseline predictors for the mean reduction (improvement) of central macular thickness.

Variable β Wald Chi-Square P-value
Sex
 Female -0.068 0.465 0.495
 Male (ref.)
Age 0.006 2.053 0.152
Diffuse retinal thickening
 3-6mm 0.104 0.756 0.384
 1-3mm 0.149 1.864 0.172
 ≤1mm -0.108 3.542 0.060
 0mm (ref.)
ONL cyst size
 Giant 0.069 1.080 0.299
 Large 0.035 0.381 0.537
 Small -0.165 1.908 0.167
 No (ref.)
IS-OS continuity
Completely disrupted -0.396 2.034 0.154
Partially continuous -0.138 16.392 <0.001
Completely continuous (ref.)
HRF foci-quantity
 Many (≥11) & all layers 0.102 1.130 0.288
 Many (≥11) & OPL-ELM -0.076 0.037 0.847
 Many (≥11) & ILM-INL 0.013 0.037 0.848
 Few (2-10) & all layers 0.140 2.062 0.151
 Few (2-10) & OPL-ELM 0.227 0.348 0.555
 Few (2-10) & ILM-INL 0.072 1.666 0.197
Absent (ref.)
Vitreomacular interface
 VMT 0.259 5.938 0.015
 VMA 0.083 0.845 0.358
 PVD (ref.)
ERM
 Yes 0.215 5.921 0.015
 No (ref.)
DR type
 PDR -0.216 1.631 0.202
 Severe NPDR -0.121 0.555 0.456
 Moderate NPDR (ref.)
SRD
 Yes 0.010 0.005 0.945
 No (ref.)

ELM, external limiting membrane; ERM, epiretinal membrane; ref, reference; HRF, hyperreflective foci; ILM, internal limiting membrane; IS-OS, inner segment-outer segment; NPDR, non- proliferative diabetic retinopathy; ONL, outer nuclear layer; OPL, outer plexiform layer; PDR, proliferative diabetic retinopathy; PVD, posterior vitreous detachment; SRD, serous retinal detachment; VMA, vitreomacular adhesion; VMT, vitreomacular traction; β, beta coefficient.