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. 2023 May 17;14:1148209. doi: 10.3389/fimmu.2023.1148209

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Copyright © 2023 Mehdi, Pusapati, Anwar, Lohana, Kumar, Nandula, Nawaz, Tracey, Yang, LeRoith, Brownstein and Roth

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diet and obesity may lead to dysregulated arginine metabolism and increase the production of advanced glycation end products (AGE) with subsequent activation of their receptor (RAGE), contributing to inflammation and asthma. The enhancing GLP-1 pathway may be the key to reducing this inflammation (148). Figure modified from articles 147 (Figure from Open access (Journal of Immunology Research) permissible to re-use under a CC-BY 4.0 license).