Table 3.
Prevalence of patient classification based on osteosarcopenia.
| NONS n=46 | OP alone n=13 | SP alone n=21 | OS n=23 | |
|---|---|---|---|---|
| Age (year) | 52.04 ± 15.24 | 60.7 ± 17.76 | 68.2 ± 14.59* | 66.82 ± 10.64 |
| Female, n (%) | 24 (52.2%) | 12 (92.3%)‡ | 9 (42.9%)†§ | 19 (82.6%)‡ |
| Dialysis vintage (years) | 5 (3,6) | 5 (2.5,8.5) | 8 (4.2,10) | 4 (3,8) |
| BMD (g/cm2) | ||||
| lumbar spine | 1.07 ± 0.17†§ | 0.81 ± 0.15*‡ | 1.14 ± 0.3†§ | 0.84 ± 0.14*‡ |
| femoral neck | 0.83 ± 0.12†§ | 0.61 ± 0.07*‡ | 0.78 ± 0.11†§ | 0.64 ± 0.1*‡ |
| total hip | 0.88 ± 0.13†§ | 0.64 ± 0.08 *‡ | 0.85 ± 0.13†§ | 0.68 ± 0.11*‡ |
| BMI (kg/m2) | 22.85 ± 3.23 | 23.65 ± 4.41§ | 22.6 ± 3.34 | 21.25 ± 2.67† |
| ASMI (kg/m2) | 6.77 ± 1.21‡ | 6.15 ± 0.76§ | 5.71 ± 0.85* | 5.08 ± 0.92*† |
| HGS (kg) | 22.91 ± 8.77‡ | 19.14 ± 5.73§ | 15.07 ± 5.04* | 12.34 ± 4.97*† |
| Calcium (mmol/L) | 2.45 ± 0.25 | 2.34 ± 0.25 | 2.36 ± 0.21 | 2.35 ± 0.22 |
| Magnesium (mmol/L) | 1.07 ± 0.15 | 1.12 ± 0.14 | 1.01 ± 0.15 | 1.05 ± 0.14 |
| Phosphorus (mmol/L) | 1.82 ± 0.39 | 1.93 ± 0.46‡ | 1.79 ± 0.59† | 1.87 ± 0.52 |
| 25 (OH)D (nmol/L) | 53.79 ± 20.49† | 37.85 ± 9.81* | 49.16 ± 18.72 | 49.57 ± 20.6 |
| PTH (pmol/L) | 28.89 (15.19,56.76) |
18.36 (13.62,37.3) |
27.07 (7.95,59.41) |
22.56 (11.42,43.29) |
| ALP (IU/L) | 79 (58.5,95.5) |
77 (63,108.5) |
99 (75,133.5) |
77 (62,115) |
| CRP (mg/L) | 4.79 (2.48,7.28) |
3.18‡
(1.37,6.84) |
5.71†§
(4.18,18.55) |
3.13‡
(2.21,6.23) |
| Albumin (g/L) | 42.51 ± 4.46§ | 41.89 ± 3.91 | 40.82 ± 6.32 | 40.93 ± 3.51* |
| Diabetes, n (%) | 11 (24.4%) | 1 (7.7%)‡ | 11 (52.4%)† | 8 (34.8%) |
| Cardiovascular disease, n (%) | 6 (13.1%) | 2 (15.4%) | 8 (38.1%) | 3 (13%) |
| Fracture history, n (%) | 2 (4.3%)†§ | 4 (30.8%) * | 5 (23.8%) | 9 (39.1%) * |
| Mortality, n (%) | 6 (13.0%)ठ| 2 (15.4%) | 10 (47.6%) * | 12 (52.2%) * |
*, significant difference from normal; †, significant difference from osteoporosis only; ‡, significant difference from sarcopenia only; §, significant difference from osteosarcopenia.
NONS, nonosteoporosis&nonsarcopenia; OP, osteoporosis; SP, sarcopenia; OS, osteosarcopenia; BMD, bone mineral density; ASMI, appendicular skeletal muscle mass index; HGS, handgrip strength; BMI, body mass index; PTH, parathyroid hormone; ALP, alkaline phosphatase; 25 (OH)D, 25-hydroxyvitamin D; CRP, C-reactive protein.