Table 2.
Comparison of patient characteristics based on the mode of HCC diagnosis
| Patient characteristics | Overall (n = 1712) | Surveillance (n = 535) | Symptomatic (n = 1177) | P value |
|---|---|---|---|---|
| Age, median (IQR) | 63 (55–71) | 63 (56–70) | 63 (55–71) | 0.992 |
| Eastern cooperative oncology group (ECOG) status | ||||
| 0–1 | 1163 (73.1%) | 475 (94.4%) | 688 (63.3%) | <0.001 |
| 2–4 | 427 (26.9%) | 28 (5.6%) | 399 (36.7%) | |
| Etiology of underlying liver disease | ||||
| HBV | 1134 (66.2%) | 351 (65.6%) | 783 (66.5%) | |
| HCV | 77 (4.5%) | 31 (5.8%) | 46 (3.9%) | |
| HBV/HCV | 56 (3.3%) | 7 (1.3%) | 49 (4.2%) | |
| Alcohol | 83 (4.8%) | 34 (6.4%) | 49 (4.2%) | |
| Autoimmune | 9 (0.5%) | 5 (0.9%) | 4 (0.3%) | |
| Cryptogenic/NASH | 353 (20.6%) | 107 (20%) | 246 (20.9%) | |
| HBV related | 1190 (69.5%) | 358 (66.9%) | 832 (70.7%) | 0.116 |
| Non‐HBV related | 522 (30.5%) | 177 (33.1%) | 345 (29.3%) | |
| Viral | 1267 (74.0%) | 389 (72.7%) | 878 (74.6%) | 0.409 |
| Non‐viral | 445 (26.0%) | 146 (27.3%) | 299 (25.4%) | |
| Ascites | ||||
| None | 1140 (67.8%) | 447 (85.3%) | 693 (59.8%) | <0.001 |
| Mild or severe | 542 (32.2%) | 77 (14.7%) | 465 (40.2%) | |
| Encephalopathy | ||||
| None | 1636 (97.1%) | 510 (97.5%) | 1126 (97.0%) | 0.784 |
| Grade I/II | 39 (2.3%) | 11 (2.1%) | 28 (2.4%) | |
| Grade III/IV | 9 (0.5%) | 2 (0.4%) | 7 (0.6%) | |
| Child‐Pugh status | ||||
| A | 898 (54.2%) | 393 (76.3%) | 505 (44.2%) | <0.001 |
| B or C | 759 (45.8%) | 122 (23.7%) | 637 (55.8%) | |