Table 3.
Unadjusted and Adjusted Quantile Regression Models of Median Change in Plasma Biomarkers
| Biomarker | Group | Baseline Median (IQR)# | Unadjusted | Adjusted+ |
|---|---|---|---|---|
| Coefficient (95% CI) p-value | Coefficient (95% CI) p-value | |||
| IL6 (pg./mL) | Control | 3.20 (1.50) | Reference | |
| Exercise | 2.65 (2.10) | −0.20 (−1.63 – 1.23) p = 0.780 | 0.67 (−0.79 – 2.13) p = 0.360 | |
| Exercise + CST | 3.10 (2.30) | −0.10 (−1.33 – 1.13) p = 0.871 | 0.32 (−0.91 – 1.54) p = 0.602 | |
| IL10 (ng/mL) | Control | 2.39 (1.91) | Reference | |
| Exercise | 2.25 (1.48) | 0.31 (−0.50 – 1.12) p = 0.446 | 0.24 (−0.54 – 1.02) p = 0.543 | |
| Exercise + CST | 2.61 (1.57) | 0.53 (−0.17 – 1.23) p = 0.136 | 0.30 (−0.39 – 0.99) p = 0.385 | |
| TNF-α (pg./mL) | Control | 7.80 (3.80) | Reference | |
| Exercise | 7.40 (2.90) | −2.70 (−4.16 – −1.24) p <0.001 | −2.71 (−4.80 – −0.62) p = 0.012 | |
| Exercise + CST | 8.90 (3.80) | −0.70 (−1.93 – 0.53) p = 0.257 | −1.74 (−3.43 – −0.06) p = 0.043 | |
| GDF-15 (pg./mL) | Control | 943.15 (1083.90) | Reference | |
| Exercise | 907.60 (786.70) | 333.70 (−394.09 – 1061.49) p = 0.362 | 129.29 (−361.58 – 620.17) p = 0.597 | |
| Exercise + CST | 943.30 (933.40) | −35.70 (−662.52 – 591.52) p = 0.909 | −164.61 (−583.09 – 253.87) p = 0.431 | |
# No baseline differences were observed. + Adjusted for Age, Gender, Ethnicity, Education, Hypertension, Hyperlipidemia, Diabetes, Physical Activity, Polypharmacy, Cognition, IADL Impairment, Falls, Adherence and baseline values; IL-6, Interleukin 6; IL10, Interleukin 10E; TNF-α, Tumour Necrosis Factor-α; GDF-15, Growth Differentiation Factor-15.