Table 2.
mhc1-uba genes and their known role
| mhclb-uba | X. tropicalis | X. laevis (Known or putative function) | References |
|---|---|---|---|
| 1 | mhc1-uba1.1–1.2 | mhc1-uba1.L (Putative role during larval development) | (Banach et al., 2017) |
| 2 | mhc1-uba2.1–2.2 | mhc1-uba2.S | |
| 3 | mhc1-uba3 | mhc1-uba3.L | |
| 4 | mhc1-uba4 | mhc1-uba4.L (Anti-mycobacterial immunity) | (E. S. Edholm et al., 2018; Rhoo et al., 2019) |
| 5 | mhc1-uba5 | mhc1-uba5.L | |
| 6 | mhc1-uba6.1–6.2 | mhc1-uba6.1–6.3L, mhc1b-uba6.4S | |
| 7 | mhc1-uba7.1–7.6 (Ubiquitous expression) | mhc1-uba7.L (Ubiquitous expression including thymic stroma) | Goyos et al (unpublished data) (Goyos et al., 2011) |
| 8 | unidentified | mhc1-uba8.1–8.4L (Strict expression in lungs - mucosal immunity? | Goyos unpublished data |
| 9 | mhc1-uba9 | mhc1-uba9.L | |
| 10 | mhc1-uba10 | mhc1-uba10.1 (Anti-ranaviral immunity) mhc1-uba10.2 |
(E.-S. Edholm et al., 2015) |
| 11 | mhc1-uba11 | mhc1-uba11.L (Cancer biology) | (Haynes-Gilmore et al., 2014) |
| 12 | mhc1-uba12 | unidentified | |
| 13 | mhc1-uba13.1–13.5 | mhc1-uba13.1, mhc1b-uba13.5.L | |
| 14 | mhc1-uba14 | mhc1-uba14 (Strict expression in the intestine - mucosal immunity?) | Edholm et al. (unpublished data) |
| 16 | mhc1-uba16.1–16.4L | Unidentified | |
| 17 | mhc1-uba17.L | unidentified |