Skip to main content
. 2022 Oct 6;108(6):1530–1543. doi: 10.3324/haematol.2022.280685

Figure 4.

Figure 4.

Quantification of cytomegalovirus-specific T cells by Dextramer staining correlates with functional assays. (A, B) Concordance between cytomegalovirus (CMV)-specific T-cell quantification by the Dextramer assay (positivity threshold 0.5 cells/mL) and either IFN-γ ELISpot for CMV (A, positivity threshold 1.75 sport-forming cells/mL after CMV antigen stimulation) or QuantiFERON-CMV (B, positivity threshold 0.2 IU/mL in the CMV antigen tube). (C, D) Linear regression analysis between CMV-specific CD8+ T cells quantified by the Dextramer assay and the presence of functional IFN-γ producing CMV-specific T lymphocytes detected by either IFN-γ ELISpot (C) or QuantiFERON-CMV (D). CMVag: cytomegalovirus antigen; sfc: spot-forming cells; IFN: interferon.